The NC3R’s Board is Recruiting!
Please find details about the recruitment process here.
IVTS and AIVT Join Forces
The IVTS is now the officially affiliated society of the Applied In Vitro Toxicology (AIVT) journal. Please read more about the AIVT here.
Inhaled Particles XII
The Inhaled Particles Conference will be in Glasgow from 25 – 27.09.2017. Deadline for abstract submission is 31.05.2017. Please click here for further details.
Practical Application of Toxicology in Drug Development
- Co-organised by the British Toxicology Society and the American College of Toxicology
- July 17–21, 2017, Cambridge, UK (Early Bird Registration deadline: May 25th)
- For more information and to register, please click here.
HESI Annual Scientific Meeting
June 13-15, Dublin, Ireland
The Health and Environmental Sciences Institute (HESI) is an international non-profit public private partnership engaged in collaborative scientific research to help resolve human and environmental health challenges. This year it will be holding its annual scientific meeting in Dublin. Registration is complimentary for delegates from academia, research institutes, foundations and government. To read more click here.
Human Tissue in Safety Assessment 2017 Survey
The NC3Rs and the Safety Pharmacology Society have previously conducted a survey into the use of human tissue in safety pharmacology. The survey results demonstrated the barriers to development, adoption and wider uptake of human tissue models as well as providing examples of potential solutions. We are following this up with a new survey three years on, to assess progress in this area.
Directed at companies carrying out safety assessment of drugs or chemicals, the aim of the survey is to:
– Assess the implementation of human tissue use in safety assessment;
– Identify the remaining barriers to development and adoption of these models;
– Identify further opportunities for sharing/learning of experiences.
The survey takes approximately 20 minutes to complete. Every reply is vital, so please get involved in this important exercise by clicking here.
IVTS-Poster-Prize at BTS 2017
In drug design it is very important to exclude unfavourable kinetics, such as accumulation in certain organelles, cells and tissues, as this is often associated with adverse effects (e.g. phospholipidosis). There are already many in vitro / in silico approaches trying to deal with these issues, however, many lack a global applicability domain. Therefore we would like to congratulate Luther J. Davis and his colleagues for their novel approach described in their excellent poster “Development of a high throughput assay to screen cationic amphiphilic compounds for effects on TFEB-mediated lysosomal stress response”. With this poster Luther J. Davis won the IVTS-Poster-Prize at this year’s BTS, which includes £200 and an invitation to present at the IVTS2017. Congratulations!